Diazepam
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|
| Systematic (IUPAC) name
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| 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one[1]
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| Clinical data
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| Trade names
|
Valium, Vazepam, others[1]
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| AHFS/Drugs.com
|
Monograph
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| MedlinePlus
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a682047
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| Licence data
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US FDA:link
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| Pregnancy cat.
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C (AU) D (US)
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| Legal status
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Prescription Only (S4) (AU) Schedule IV (CA) P.O.M otherwise Class C (UK) Schedule IV (US) Psychotropic schedule IV (UN) ℞ Prescription only
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| Dependence liability
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Moderate
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| Routes
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By mouth, IM, IV, rectal
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| Pharmacokinetic data
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| Bioavailability
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76% (64–97%) by mouth, 81% (62–98%) rectal[2]
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| Metabolism
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Liver—CYP2B6 (minor route) to desmethyldiazepam, CYP2C19 (major route) to inactive metabolites, CYP3A4 (major route) to desmethyldiazepam
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| Half-life
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(50 hours); 20–100 hours (36–200 hours for main active metabolite desmethyldiazepam)
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| Excretion
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Kidney
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| Identifiers
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| CAS number
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439-14-5  Y[??]
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| ATC code
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N05BA01
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| PubChem
|
CID 3016
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| IUPHAR ligand
|
3364
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| DrugBank
|
DB00829
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| ChemSpider
|
2908 Y
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| UNII
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Q3JTX2Q7TU Y
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| KEGG
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D00293 Y
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| ChEBI
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CHEBI:49575 Y
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| ChEMBL
|
CHEMBL12 Y
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| Chemical data
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| Formula
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C16H13ClN2O
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- CN1C2=C(C(C3=CC=CC=C3)=NCC1=O)C=C(Cl)C=C2
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InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 Y
Key:AAOVKJBEBIDNHE-UHFFFAOYSA-N Y
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 N (what is this?) (verify)
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Diazepam (ඩයෑසපෑම්) යනු බෙන්සොඩයසපීන (benzodiazepine) පවුලට අයත් ඖෂධයකි.[3] [4]
[??]
(what is this?) (verify)
