Chlorphenamine

Chlorphenamine
Systematic (IUPAC) name
	3-(4-Chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine
Clinical data
Trade names	Chlor-Trimeton; Piriton
AHFS/Drugs.com	Monograph
MedlinePlus	a682543
Pregnancy cat.	A (AU) B (US)
Legal status	Pharmacist Only (S3) (AU) P (UK) OTC (US)
Routes	By mouth, IV, IM, SC
Pharmacokinetic data
Bioavailability	25 to 50%
Protein binding	72%
Metabolism	Hepatic (CYP2D6)
Half-life	13.9–43.4 hours
Excretion	Renal
Identifiers
CAS number	113-92-8 [??]
ATC code	R06AB04
PubChem	CID 2725
IUPHAR ligand	1210
DrugBank	DB01114
ChemSpider	2624
UNII	3U6IO1965U
KEGG	D07398
ChEBI	CHEBI:52010
ChEMBL	CHEMBL505
Chemical data
Formula	C16H19ClN2
	InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 ; Key:SOYKEARSMXGVTM-UHFFFAOYSA-N ;
Physical data
Solubility in water	0.55 g/100 mL, liquid mg/mL (20 °C)
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Chlorphenamine ( chlorpheniramine, CP, හෝ CPM) යනු පළමු පරම්පරාවේ ප්‍රතිහිස්ටමින් (first-generation antihistamine) ඖෂධයකි.

මූලාශ්‍ර

^ Yasuda SU, Wellstein A, Likhari P, Barbey JT, Woosley RL (1995). "Chlorpheniramine plasma concentration and histamine H1-receptor occupancy". Clin. Pharmacol. Ther. 58 (2): 210–20. doi:10.1016/0009-9236(95)90199-X. PMID 7648771.

මෙම ලිපිය තවමත් අංකුර ලිපියකි. විකිපීඩියාවට උදවුවක් ලෙසින් ඔබ හට එය විහිදුවාලිය හැක.